Temporarily relieves cold & flu symptoms so you can rest easy with Tylenol Extra Strength Cold + Flu Multi-Symptom Night Liquid Cold Medicine. From the #1 doctor recommended pain relief brand, this extra strength night cold & cough medicine with a frosted berry flavor temporarily reduces fever & relieves common cold & flu symptoms including minor body aches & pains, headache, sore throat, & cough. Each 30-milliliter dose of the liquid medicine contains 1,000 milligrams of acetaminophen, a pain reliever & fever reducer; 30 milligrams of dextromethorphan HBr, a cough suppressant; & 12.5 milligrams of doxylamine succinate, an antihistamine. For adults & children 12 & over for cough & sore throat relief at night, this product includes a dosing cup. Take 30 mL in the dosing cup provided every 6 hours while symptoms last do not take more than 90 milliliters in 24 hours, unless directed to do so by a doctor. (Based on a survey IQVIA 2025).