Compare to Imodium Multi-Symptom Relief active ingredients. Don’t let symptoms of diarrhea plus cramps and pressure, bloating and gas derail your day. Loperamide Hydrochloride and Simethicone Caplets, 2 mg/125 mg (capsule-shaped tablets) provides two medications for multi-symptom relief for adults and children ages 6 years and older. Active ingredients are loperamide hydrochloride 2 mg, anti-diarrheal, and simethicone 125 mg, anti-gas. Here's your multi-symptom medication choice when diarrhea, cramps and pressure, bloating and gas interfere with daily activities. This product is gluten free. Keep on hand at home in the medicine cabinet and also great to use to relieve digestive discomfort while on the go.