Alka-Seltzer Plus Severe Cold Orange Zest Effervescent Tablets offer fast and effective relief from severe cold symptoms. These tablets tackle headaches, sore throats, sinus congestion, runny nose, sneezing, fever, and body aches with a refreshing orange zest flavor. Simply dissolve two tablets in 4 ounces of water every four hours as needed to feel better fast and get back to your daily routine.